Taw qhia rau urolithin a
Urolithin A yog lub ntuj sib xyaw ua los ntawm cov metabolism ntawm cov metabolism hauv kev noj haus los ntawm plab hnyuv muaj, thiab pom nyob hauv cov zaub mov xws li pomegranates, txiv pos nphuab, thiab walnuts. Txawm li cas los xij, tsuas yog kwv yees li 40% ntawm cov pejxeem tuaj yeem hloov kho tau yooj yim rau urolithin ib qho kev sib txawv, uas ua rau muaj kev sib txawv ntawm tus kheej qhov sib txawv ntawm nws cov peev xwm[1].
Qoj Conchism: urolithin ib qho mitochondrial autophagy (mitophagy) kom tshem tawm cov hnub nyoog lossis tsim kho lub voj voog "ntawm cov metabolism hauv lub zog[2]Cov txheej txheem .Qhov no tsis tsuas yog qeeb cell kev laus, tab sis kuj tseem muaj feem cuam tshuam nrog kev tiv thaiv kev tiv thaiv thiab kev txhim kho ntau yam kab mob.
Cov txiaj ntsig zoo ntawm urolithin a
1. Los tiv thaiv kev laus thiab xovtooj ntawm tes
Mitochondrial muaj nuj nqi los ntawm kev cai:
Nyob rau hauv cov qauv tsiaj, urolithin ua rau cov leeg nqaij slougle thiab cov nas laus los ntawm kev txhawb nqa mitochondrial autophagy[3].
Daim tawv nqaij Noj Qab Haus Huv:
Nyob rau hauv cov kev sim vito tau pom tias Urolithin A yuav txo UV-ua rau tawv nqaij puas tsuaj, tab sis tib neeg cov pov thawj tsis yog[4].
2. Cov leeg noj qab haus huv thiab kev siv dag zog
Txhim kho cov leeg ua kom nce qib:
Kev mus kuaj mob (NCT03464500) Rau cov neeg laus uas tau pom tias tom qab urolithin a rau kev ua kom ntev txhua hnub, xws li taug kev nrawm thiab tuav lub zog txhim kho[5].
3. Metabolism thiab cov kev cai o
Anti-inflammatory nyhuv:
Kev sim ntawm tes tau pom tias Urolithin ib qho tuaj yeem txo qhov kev tso tawm ntawm cov kev tso tawm ntawm cov pro-incammatory (xws li tib neeg txoj kev tshawb fawb tseem nyob rau thaum ntxov[6].
Cov teebmeem metabolic:
Cov kev tshawb fawb tsiaj tau qhia tias nws yuav txhawb cov rog rog, tab sis muaj qhov tsis muaj cov ntaub ntawv tswj qhov hnyav tib neeg los txhawb qhov no[7].
4. Lwm Yam Kev Tshawb Fawb
Neuroproction:
Txhim kho kev txawj ntse kev txawj ntse tau pom nyob rau hauv nas tus qauv ntawm Alzheimer tus kab mob, tab sis tib neeg txoj kev cuam tshuam tsis tau paub tseeb[8].
Kev Tshawb Fawb Cancer:
Txwv rau hauv vitro cell sim thiab tsis tau mus txog theem daim ntawv thov kho mob[9].
Yuav ua li cas kom tau urolithin ua tau zoo?
Kev Noj Qab Haus Huv:
Cov khoom noj muaj cov zaub mov ellagitannins xws li pomegranate kua txiv, txiv pos nphuab, thiab walnuts, tab sis lawv yuav tsum tau cia siab rau cov hnyuv rog rau kev hloov dua siab tshiab.
Kev Pab Txhawb Ntxiv:
Rau cov uas muaj peev xwm muaj peev xwm hloov dua siab tshiab, urolithin ib qho kev pab (250mg {{
Ua ke Synergy:
Ua ke nrog cov khoom xyaw los tiv thaiv xws li vitamin d thiab omega -3, nws tuaj yeem txhim kho los tiv thaiv kev laus thiab kev tswj hwm kev laus.
Tag
Qhov kev tshawb pom ntawm urolithin ib tug qhia qhov sib sib zog nqus ntawm plab hnyuv uas muaj kev sib sib zog nqus thiab tib neeg kev noj qab haus huv, thiab tseem muaj lub tswv yim tshiab rau kev tswj hwm tus kab mob. Seb nws yog cov neeg laus uas txaus siab rau kev ua kis las, lossis cov neeg noj qab haus huv cov neeg muaj teeb meem los ntawm cov teeb meem kis las los ntawm cov teeb meem kis las los ntawm cov teeb meem kis las ncaws pob, urolithin A tau qhia txog cov peev xwm rau cov kev cuam tshuam rau kev nkag siab. Nyob rau yav tom ntej, nrog kev tshawb fawb txog cov kws kuaj mob no yuav dhau los ua cov khoom siv tseem ceeb rau cov neeg noj khoom haus zoo rau tus kheej thiab muaj zog ntxiv "hauv txoj kev science ntau dua.
Ntawv Sawv cev
[1] Tomás-Barberán, FA, li al. (2017). Out Microbiota metabolism ntawm pomegranate ellagitannins: urolithin ntau lawm. Khoom noj & muaj nuj nqi, 8 (12), {5}}.
[2] Ryu, D., li al. (2016). Urolithin yog ntxias mitophagy thiab ntev lifespan hauv C. Elegans. Xwm metabolism, 18 (5), {4 4}}.
[3] Andreux, PA, li al. (2019). Lub mitophagy activator urolithin A yog qhov muaj kev nyab xeeb thiab tsim cov molecular kos npe ntawm kev kho mob mitocondrial thiab kev noj qab haus huv ntawm tsev neeg. Xwm metabolism, 1 (6), {4 4}}.
[4] Paller, CJ, li al. (2021). Kev tshuaj xyuas ntawm pomegranate ellagitannins thiab urolithins hauv kev noj qab haus huv tawv nqaij. Phau ntawv Journal of Termmetic Dermatology, 20 (3), {4 4}}.
[5] Liu, S., li al. (2021). Cov nyhuv ntawm urolithin ib qho kev txhawb nqa ntawm cov leeg ua kom huv thiab mitochondrial kev noj qab haus huv nyob rau hauv cov neeg laus: Randedized kev kuaj mob. Jama Network qhib, 4 (8), E2124396.
[6] Singh, A., li al. (2020). Urolithin ib qho kev ua kom muaj zog, kev siv dag zog, thiab kev kho mob ntawm mitochondrial kev noj qab haus huv hauv cov laus uas muaj hnub nyoog nruab nrab. Cov Ntawv Qhia Txog Cell, 1 (5), 100097.
[7] Zhao, J., li al. (2022). Urolithin ib qho kev txhawb nqa xim av ua kom muaj zog thiab txo cov kev rog ua kom muaj kev rog. Ntshav qab zib, 71 (2), {5}}.
[8] KuJ Muaskska, M., li al. (2021). Cov kua txiv ntshauv ntawm cov kua txiv pomegranate tawm tsam cov kab mob Parkinson thiab Alzheimer tus kab mob. Assients, 13 (2), 599.
[9] Sharma, M., li al. (2020). Urolithin A suppresses cell proliferation thiab induces apoptosis hauv tib neeg cov kab mob cancer mis. Carcinogenesis, 41 (12), 1695-1704.
DISCLAIMER: Cov ntawv sau saum toj no yog txhua yam los ntawm kev tshawb fawb cov ntaub ntawv tshawb fawb thiab Is Taws Nem thiab tsis tau raug soj ntsuam los ntawm cov chaw muaj tswv yim hauv tebchaws. Kab lus no tsis yog xav kuaj, kho, kho lossis tiv thaiv ib tus kabmob. Yog tias muaj kev cuam tshuam lossis tsis nkag siab, thov hu rau peb kom muab tshem tawm. Ua tsaug.